SPACE PHILICLELP-1 · LIFE SCIENCE IN ORBIT

THE SATELLITE

LELP-1: design of a free-flying life-science lab

LELP-1 is a free-flying, uncrewed laboratory for life science and microgravity research. It flies 32 sealed experiment bays in a 550 km dawn-dusk orbit for as long as the longest experiment on board needs, up to 14 days, runs them automatically on signed customer commands, and brings the whole lab home under an inflatable heat shield so samples reach the customer's courier within half an hour of splashdown.

Launch mass242.6 kgof the 250 kg RUPAK allocation
Comes home222.6 kgarm, wings, antenna stay with the stage
Bays32110.6 kg of modules on this manifest
Quasi-steady g~7.3 × 10⁻⁷ gat a bay, computed below
Return7.7 g peakentry model, 4 °C held in the bays

Mission

LELP-1 is the orbital laboratory of the RUPAK system. The reusable RUPAK booster and its upper stage put the lab into a 550 km dawn-dusk sun-synchronous orbit. The upper stage stays attached during the mission: it carries the solar wings, trims the orbit and later flies the deorbit burn. Lab operations last as long as the longest protocol on the manifest (2 to 14 days). Then the robotic arm parks itself on the stage, the lab separates, inflates its 2.6 m heat shield, enters, opens its parachute at 4 km and splashes down near the recovery ship. The arm, the solar wings and the relay antenna stay with the stage, so 222.6 kg comes home and the stage breaks up over open sea.

LELP-1 in CAD

Generated from the twin by cad/build_lelp1.py (CadQuery, OpenCascade): the 32-bay stack with each bay's payload mass, the central chamber, the packed heat shield, Dexter-L on its ring track, and the RUPAK upper stage with the 600 W wings, the relay boom and the arm's grapple post (the stage is simplified context). Switch to Entry for the Return Module with its 2.6 m heat shield inflated.

CAD generated by cad/build_cad.py (CadQuery, OpenCascade kernel) from the sizing numbers: concept geometry, not a released design.

Mass properties from the solids

ConfigurationMass kgCoM z, mPrincipal inertia, kg m² Twin's estimate
In orbit: lab on the RUPAK upper stage970-1.341996 / 2019 / 191420 / 420 / 110
Return Module, heat shield inflated222.6+0.6565 / 68 / 44-

Finding. The inertia computed from the CAD is about 4.8 times the twin's earlier estimate about the transverse axes, because the upper stage's mass sits metres from the stack's centre of mass. The twin now uses the CAD values; whole-mission runs of the attitude model:

CasePeak wheel momentumMargin at peakPointing error, arm movingPeak disturbanceDumping, share of time
twin estimate (before 4 Oct 2026)91.3 %9.5 %7.2°154 µN m4.9 %
CAD, 3 x 3.5 N m s wheels86.5 %15.6 %4.2°712 µN m7.6 %
CAD, 3 x 4.0 N m s wheels74.0 %35.1 %4.2°712 µN m5.4 %

Gravity-gradient torque grows about five-fold and the magnetorquers dump more often, but Dexter-L's momentum still sizes the wheels. With 3 x 3.5 N m s wheels the margin at the peak is about 16 %, under a 25 % design target; 4.0 N m s wheels give about 35 %, at a wheel mass the vendor has to give. The larger inertia also cuts the pointing error while the arm moves from about 7° to about 4°.

What the 15 reference experiments ask, and how LELP-1 answers

The catalog's experiments are the design drivers. "Standard" is in every bay; "option" is a bay variant a customer books; "new" is a capability this design adds to LELP-1 because the experiments need it.

NeedExperimentsStatusDesign answer
Culture temperature per bay, held through re-entryStem-cell organoids, Protein crystallization for drug formulation, Antibiotic resistance of pathogenic bacteria, Seed germination and root growth, Bioreactor for tissue engineering and biomanufacturing, Microfluidic lab-on-a-chip and organ-chips, Cell mechanobiology: how cells sense gravity and load, Biofilm formation on spacecraft and medical materials, Microalgae and cyanobacteria for oxygen and food, Human heart muscle cells from stem cells, Immune T-cell activation, Bone cells: resorption and mineralization, C. elegans muscle and ageing, 3D tumour spheroids for drug testingSTANDARDEvery bay has a 25 W thermoelectric block with its own setpoint from 4 to 45 °C. Preserved samples ride home at 4 °C or at the culture temperature, through re-entry and splashdown.
Automated fluidics (media exchange, dosing, fixing, lysing)Stem-cell organoids, Protein crystallization for drug formulation, Antibiotic resistance of pathogenic bacteria, Seed germination and root growth, Bioreactor for tissue engineering and biomanufacturing, Microfluidic lab-on-a-chip and organ-chips, Cell mechanobiology: how cells sense gravity and load, Biofilm formation on spacecraft and medical materials, Microalgae and cyanobacteria for oxygen and food, Human heart muscle cells from stem cells, Immune T-cell activation, Bone cells: resorption and mineralization, C. elegans muscle and ageing, 3D tumour spheroids for drug testingSTANDARDPumps, valves and reservoirs in each bay run the customer's timeline without a crew; waste stays in a bag inside the bay's triple containment.
Imaging in orbitStem-cell organoids, Protein crystallization for drug formulation, Antibiotic resistance of pathogenic bacteria, Seed germination and root growth, Alloy solidification, Microfluidic lab-on-a-chip and organ-chips, Cell mechanobiology: how cells sense gravity and load, Microalgae and cyanobacteria for oxygen and food, Human heart muscle cells from stem cells, Bone cells: resorption and mineralization, C. elegans muscle and ageing, 3D tumour spheroids for drug testingSTANDARDA LumaScope-class microscope in the bay, or a trip on the robotic arm to the central lab's 40x fluorescence microscope. Raw frames stay on board and come home; per-well metrics are downlinked daily.
Video of moving samples (beating heart cells, swimming worms, live cytoskeleton)Human heart muscle cells from stem cells, C. elegans muscle and ageing, Cell mechanobiology: how cells sense gravity and load, Microfluidic lab-on-a-chip and organ-chipsOPTIONThe bay imager records short video clips at video rate; the analysis (beat rate, body bends, fibre movement) runs on board and only the numbers and selected clips are downlinked. No arm moves during recording.
Light for photosynthesisSeed germination and root growth, Microalgae and cyanobacteria for oxygen and foodNEWA lit bay variant with an LED growth panel and a light sensor on a day-night timer inside the large-bay power limit, plus a gas-permeable vent so oxygen from photosynthesis does not build up.
Live samples loaded late and kept powered through launchStem-cell organoids, Protein crystallization for drug formulation, Antibiotic resistance of pathogenic bacteria, Bioreactor for tissue engineering and biomanufacturing, Microfluidic lab-on-a-chip and organ-chips, Biofilm formation on spacecraft and medical materials, Microalgae and cyanobacteria for oxygen and food, Human heart muscle cells from stem cells, C. elegans muscle and ageingNEWBays are loaded through an access panel up to 24 h before launch (48 h for mature bioreactor tissue). A pad umbilical powers the bay blocks until liftoff and the lab battery carries them through ascent until the solar wings deploy (orbit insertion is about 47 min after liftoff in the twin). Cryopreserved cells keep the passive -80 °C cassette.
A 1 g control in orbitCell mechanobiology: how cells sense gravity and load, Immune T-cell activation, Antibiotic resistance of pathogenic bacteria, Stem-cell organoids, Microalgae and cyanobacteria for oxygen and food, Bone cells: resorption and mineralization, C. elegans muscle and ageing, 3D tumour spheroids for drug testingNEWA centrifuge bay in a second large-bay slot spins a cassette at 1 g next to the microgravity samples (about 105 rpm at an 8 cm radius, our estimate), dynamically balanced and placed away from sensitive bays. It separates microgravity from radiation, launch and handling effects, which a ground control cannot do, and can also run 0.16 g (Moon) or 0.38 g (Mars). Any customer can book positions in it.
Heat above 45 °C (directional solidification)Alloy solidificationNEWTransparent model alloys fly in a large bay with their own insulated 70 °C hot zone (5.7 kg, 26 W, estimate). Metallic alloys need a furnace bay variant across two large-bay slots (700 to 800 °C, about 200 W during melt-back, about 1 to 1.5 kWh per run, estimates), with its own power line and heat path, scheduled against the 600 W array.
Frozen samples after the flightBiofilm formation on spacecraft and medical materials, Bone cells: resorption and mineralizationOPTIONBays stop at 4 °C, so protocols fix or stabilise samples to hold at 4 °C until the lab. A -80 °C freezer and dry ice on the recovery ship take samples that must be frozen from the courier handover onwards; an in-orbit freezer bay is not planned for the first flights.
Quiet microgravity during sensitive stepsProtein crystallization for drug formulation, Alloy solidification, Cell mechanobiology: how cells sense gravity and loadSTANDARDQuiet windows in the mission plan (no arm moves, steady wheel speeds) and an accelerometer log in every bay.
Fast return to the customer's labStem-cell organoids, Protein crystallization for drug formulation, Antibiotic resistance of pathogenic bacteria, Seed germination and root growth, Bioreactor for tissue engineering and biomanufacturing, Microfluidic lab-on-a-chip and organ-chips, Cell mechanobiology: how cells sense gravity and load, Biofilm formation on spacecraft and medical materials, Microalgae and cyanobacteria for oxygen and food, Human heart muscle cells from stem cells, Immune T-cell activation, Bone cells: resorption and mineralization, C. elegans muscle and ageing, 3D tumour spheroids for drug testingSTANDARDThe whole lab splashes down next to the recovery ship; each bay goes to its customer's courier with a signed custody ledger about 20 minutes after splashdown.
Containment of microbes and human cellsAntibiotic resistance of pathogenic bacteria, Biofilm formation on spacecraft and medical materials, Stem-cell organoids, Human heart muscle cells from stem cells, Immune T-cell activation, 3D tumour spheroids for drug testing, Microfluidic lab-on-a-chip and organ-chipsSTANDARDBSL-2 triple containment in every bay, pressure and seal monitoring, automatic isolation of a leaking bay.

The experiment bay

Medium bayLarge bay
Payload mass3.3 kg6.0 kg
Peak power15 W30 W
Culture cassette12 wells24 wells
Temperature25 W thermoelectric block, any setpoint from 4 to 45 °C, held through re-entry
Servicesautomated fluidics (pumps, valves, reservoirs for media, drugs, fixative and lysis buffer, waste bag); an optional LumaScope-class inverted microscope (brightfield and two fluorescence channels); active silicon dosimeter and passive TLDs; temperature, pressure, humidity and acceleration sensors; a passive -80 °C cassette for cryopreserved launch, loaded 24 h before launch; transfer by the robotic arm to the central lab's 40x fluorescence microscope.
ContainmentBSL-2 triple containment, pressure and seal monitoring, isolation on a leak
Controlyour own signed commands (start, preserve, arm tasks), checked by Sentinel; operator can power or isolate a bay but not run your protocol

Environment in the bays

Microgravity, quasi-steady

SourceLevelBasis
Atmospheric drag6.0 × 10⁻⁹ gdensity 3e-13 kg/m³ (moderate solar activity), 3 m² side area, Cd 2.2, 962 kg lab and upper stage
Gravity gradient7.3 × 10⁻⁷ g3n²d for a bay 2 m from the stack's centre of mass (estimate), along the local vertical
Rotation with the orbit2.4 × 10⁻⁷ gn²d, only if the stack turns once per orbit to stay Earth-pointing

Quasi-steady accelerations at a bay are below one millionth of Earth's gravity in the twin's numbers and are set by the gravity gradient, because the bays sit about 2 m from the centre of mass of the lab and upper-stage stack; drag at 550 km is about a hundred times smaller. That is the same order as the ISS's quasi-steady level, so a free-flyer's real gain is in vibration and transients: no crew, no dockings, no station machinery. LELP-1 has its own disturbances: in the twin the robotic arm shakes the lab to about 10⁻⁴ to 10⁻³ g while it moves (estimate), and reaction wheels and pumps add vibration. The mission plan therefore keeps quiet windows (no arm moves during crystallisation, solidification or mechanobiology steps), and every bay logs its own acceleration so customers see what their samples felt. These LELP-1 levels are model estimates until a bay accelerometer flies.

Radiation

The twin's dosimeter model gives about 0.6 mGy per day inside a bay at 550 km, with about six South Atlantic Anomaly passes a day, so a 7-day flight collects a few mGy. Measured doses inside the ISS Columbus module were about 0.2 to 0.36 mGy per day (table below), so the model is 1.7 to 3 times higher: plausible for a higher orbit with less shielding, but a model value until the dosimeter flies. Every bay logs its own dose from lab power-on to entry, and passive TLDs integrate the whole flight. A few mGy is far below the doses of most in-vitro radiation studies, so on LELP-1 microgravity dominates the space-versus-ground difference; a 1 g centrifuge bay on board separates the two.

The environment compared with earlier platforms

WhatValue
ISS quasi-steady acceleration (below 0.01 Hz)On the order of less than 1 micro-g; mainly from aerodynamic drag and vehicle rotation14
ISS vibratory acceleration without isolationSpectrum runs from much less than 1 micro-g below 0.1 Hz to well over 10 milli-g at high frequency; payload isolation can cut it by up to a factor of 10014
ISS absorbed dose rate inside Columbus (DOSIS 2009-2011, DOSIS 3D from 2012)195-270 microGy per day (2010 minimum) to 260-360 microGy per day (2012 maximum), i.e. about 0.2-0.36 mGy per day; varies with solar activity, ISS altitude and shielding15
Comparison with LELP-1 estimateOur model value of about 0.6 mGy per day at 550 km is about 1.7 to 3 times the ISS Columbus values. Higher is the expected direction (higher altitude, lighter shielding), but no opened source gives a free-flyer number at 550 km. Treat 0.6 mGy per day as our estimate until checked.15
Free-flyer radiation measured on a biosatelliteBion-M No.1 carried an RD3-B3 radiometer-dosimeter at 253-585 km in April-May 2013; dose-rate numbers not in the opened record18
Altitude of other recent platformsPOEM-4 at about 350 km; The Exploration Company Mission Possible at 550 km (same altitude as LELP-1)1016
Free-flyer microgravity levelNo opened source gave a measured quasi-steady level for Bion-M, Foton-M or SJ-10. The LELP-1 figure (about 1e-6 g near the centre of mass) is our design estimate, not a sourced benchmark.

Sources

  1. ISRO, CROPS: A Leap in Space Biological Experiments https://www.isro.gov.in/CROPS.html
  2. NASA, A Researcher's Guide to: Acceleration Environment (NP-2015-11-040-JSC) https://www.nasa.gov/wp-content/uploads/2016/06/acceleration-environment-iss-mini-book_detail-508c.pdf
  3. Berger T et al., 2016, DOSIS & DOSIS 3D: long-term dose monitoring onboard the Columbus Laboratory of the International Space Station (ISS), Journal of Space Weather and Space Climate, doi:10.1051/swsc/2016034 https://elib.dlr.de/107982
  4. The Exploration Company, 2025, Mission Possible: re-entry milestone achieved for Europe's reusable spaceflight https://exploration.space/blog/mission-possible-re-entry-milestone-achieved-for-europes-reusable-spaceflight
  5. Dachev TP et al., 2015, BION-M No. 1 spacecraft radiation environment as observed by the RD3-B3 radiometer-dosimeter in April-May 2013, Journal of Atmospheric and Solar-Terrestrial Physics 123:82-91, doi:10.1016/j.jastp.2014.12.011 https://cris.fau.de/publications/106622384?lang=de_DE

Lessons from earlier platforms

From the platform benchmark on the overview; sources there.

Subsystems

Chips show where each number comes from: TEAM a team document, TWIN the twin's own design, EST an engineering estimate, TBD open. Hover for the source.

Orbit550 km TEAM dawn-dusk sun-synchronous, inclination 97.6 deg EST, period 95.6 min
Powersolar wings 600 W TWIN at beginning of life, battery 1500 Wh TWIN, 28 V EST bus. The dawn-dusk orbit keeps the arrays in sunlight most of the year; it crosses the Earth's shadow only from 03 May to 09 August, at most 22 min per orbit (23 %).
Thermallab held near 21 C EST by a 0.85 m2 EST radiator and heaters; each bay's own thermoelectric block sets its culture temperature. Team bands: mammalian 36.5 to 37.5 C TEAM, microbial 22 to 37 C TEAM, plants 20 to 23 C TEAM, cryo -80 to -20 C TEAM
Attitude3 reaction wheels of 3.5 N m s EST sized for the robotic arm's momentum, star tracker, magnetorquers of 20 A m2 EST for momentum dumping
Dataon-board computer ARM Cortex-A, cFS or F Prime TEAM, 256 GB EST storage for imaging archives that come home with the lab
CommunicationsS-band TT&C through ISTRAC at 32,000 bit/s TWIN down; X-band science through Leuk (Switzerland) 2,000,000 bit/s TWIN and ESOC (Germany) 1,500,000 bit/s TWIN; inter-satellite relay 600,000 bit/s TWIN
Propulsionnone on the lab: the RUPAK upper stage stays attached, trims the orbit and flies the 150 m/s TWIN deorbit burn (Isp 330 s TEAM)
Return2.6 m inflatable heat shield (4 tori, packed 1.1 m), 223 kg at entry, peak 7.7 g and 434 kW/m² in the twin's entry model, 9 m main parachute at 4 km, splashdown at 7.9 m/s
Command securitySentinel: every command signed with ML-DSA-87 (post-quantum), checked against ownership and lab rules, and screened by a mission guardian; customers can only command their own bays

Mass budget

ItemkgReturn
experiment modules (32: 6 kg large, 3 kg medium class)110.6comes home
lab structure, entry-rated module latches34.0comes home
central chamber, translation rig, sensors10.0comes home
avionics, radios, Sentinel crypto unit, harness, beacons13.0comes home
battery 1.5 kWh10.0comes home
ADCS: 3 x 3.5 N m s wheels sized for the arm, star tracker, magnetorquers11.0comes home
thermal control6.0comes home
HIAD: 4 tori and straps6.0comes home
HIAD: flexible TPS (ceramic fabric, insulator, gas barrier)6.0comes home
HIAD: rigid nose and centerbody TPS6.0comes home
HIAD: inflation system (2 kg N2, bottle, valves)5.0comes home
main parachute 9 m, mortar, riser5.0comes home
Dexter-L arm and controller (parks on the upper stage)12.0stays with the upper stage
solar wings 600 W (stay on the upper stage)7.0stays with the upper stage
ISL antenna boom (stays on the upper stage)1.0stays with the upper stage
Launch242.67.4 kg margin to 250 kg

The modules line is the 32 payload sheets in the twin's manifest. 6 kg and 3.3 kg are bay limits, not module masses: a manifest with every bay at its limit would weigh about 281 kg, so every manifest is checked against the 250 kg allocation.

Open design items